Jane Schuh

Veterinary and Microbiological Sciences
Van Es Hall, Room 187                                               

North Dakota State University
Fargo, ND 58105
Office: (701) 231-7841

Laboratory: (701) 231-7905
E-mail: Jane.Schuh@ndsu.edu

Doctorate

• Cellular and Molecular Biology, Immunology
• Major Professor: Dr. Michael Robinson
• North Dakota State University, 2000

Bachelor of Science

• Zoology
• Advisor: Dr. James Brammer
• North Dakota State University, 1992

PROFESSIONAL EXPERIENCE

2004-present

Assistant Professor of Immunology

• Veterinary and Microbiological Sciences
• North Dakota State University

2000-2004

Postdoctoral Fellow

• Department of Pathology
• University of Michigan Medical School
• Mentors: Dr. Steven L. Kunkel and Dr. Cory M. Hogaboam

SELECTED RESEARCH AND OTHER SCHOLARLY ACTIVITIES

§        Asthma and allergy research including the assessment of innate, acute, and chronic lung responses that occur during the evolution of fungus-induced airway inflammation. My laboratory utilizes experimental animal models to assess the mechanistic and molecular role of specific cytokines and chemokines during the initiation, maintenance, and resolution of the pulmonary immune response.

AWARDS AND                 HONORS                 

• Multidisciplinary Training Program in Lung Disease, Pulmonary and Critical Care Medicine, University of Michigan; 2001-2004

PROFESSIONAL    AND HONOR SOCIETIES   

• American Association of Immunologists

• American Society for Investigative Pathology

WORKSHOPS      AND FORUMS                 

 Workshops and Seminars

• Women in the Academy

Contributions and concerns of women in academic life

Presented by the Center for Research on Learning and Teaching Theatre Program. 2003.

• Getting Ready for an Academic Career: preparing future faculty conference

Insights into academic life, institutional profiles, and time organization in academe

Presented by the Center for Research on Learning and Teaching (CRLT). 2003.

• Mentoring: A Career Activity

Emphasizing the cultivation of a scientific career through mentoring

David G. Nathan, M.D. and Lydia Villa-Komaroff, Ph.D. keynote speakers

University of Michigan Medical School Biomedical Research Council. 2004.

• Writing a Grant Proposal from the Reviewer’s Perspective

Scientific grant writing seminar

Christine Black, Ph.D. presenter

University of Michigan Division of Research Development and Administration (DRDA) Sponsored Projects. 2004.

• Grant Writer’s Workshop

Scientific grant writing seminar

David Morrison, Ph.D., presenter

Sponsored by ND-BRIN. 2004.

• Cooperative Learning/Problem-Based Learning Strategies for Engaged Learning

Emphasizing learning strategies for the classroom

Ed Deckard and Brenda Deckard, presenters

North Dakota State University. 2004.

SELECTED PUBLICATION       LIST   

Peer-reviewed journal articles

•  Cory M. Hogaboam, Kazue Takahashi, R. Alan B. Ezekowitz, Steven L. Kunkel, and Jane M. Schuh. 2004. Mannose-binding lectin deficiency alters the development of fungal asthma: effects on airway response, inflammation, and cytokine profile. Journal of Leukocyte Biology. 75(5):805-14.

• Jane M. Schuh, Kate Blease, Hilke Bruhl, Matthias Mack, and Cory M. Hogaboam. 2003. Therapeutic intrapulmonary targeting of RANTES/CCL5-responsive cells prevents chronic allergic airway disease induced by Aspergillus fumigatus. European Journal of Immunology. 33(11):3080-90.

• Jane M. Schuh, Kate Blease, Steven L. Kunkel, Christine A. Power, Amanda Proudfoot, Nicholas W. Lukacs, and Cory Hogaboam. 2002. Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice. FASEB Journal. 16(10):1313-5.

• Jane M. Schuh, Kate Blease, Steven L. Kunkel, and Cory M. Hogaboam. 2002. Eotaxin/CCL11 is involved in acute, but not chronic, allergic airway responses to Aspergillus fumigatus. American Journal of Physiology-Lung Cellular and Molecular Physiology. 283(1):L198-204.

• Jane M. Schuh, Kate Blease, and Cory M. Hogaboam. 2002. The role of CC chemokine receptor 5 (CCR5) and RANTES/CCL5 during chronic fungal asthma in mice. FASEB Journal. 16(2):228-30.

• Jane M. Schuh, Kate Blease, and Cory M. Hogaboam. 2002. CXCR2 is necessary for the development and persistence of chronic fungal asthma in mice. Journal of Immunology; 168(3):1447-56.

• Kate Blease, Jane M. Schuh, Claudia Jakubzick, Nicholas W. Lukacs, Steven L. Kunkel, Bharat H. Joshi, Raj K. Puri, Mark H. Kaplan, and Cory M. Hogaboam. 2002. Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma. American Journal of Pathology, 160(2):481-90.

• Kate Blease, Claudia Jakubzick, Jane M. Schuh, Bharat H. Joshi, Raj K. Puri, and Cory Hogaboam. 2001. IL-13 fusion cytotoxin ameliorates chronic fungal-induced allergic airway disease in mice. Journal of Immunology. 167(11):6583-92.

Invited reviews and book chapters

• Jane M. Schuh, Steven L. Kunkel, and Cory M. Hogaboam. 2004. Innate and Cell-mediated Immunity in the Lung: an Aspergillus chronicle. In Fidel and Huffnagle (Eds.), Fungal Immunology from an Organ Perspective. New York; Kluwer Academic Publishers; in press.

• Jane M. Schuh, Kate Blease, Steven L. Kunkel, and Cory M. Hogaboam. 2003. Cytokines and Chemokines: axis and allies in allergic fungal asthma. Cytokines and Growth Factor Reviews. 14(6):503-10.

• Jane M. Schuh, Steven L. Kunkel, Nicholas W. Lukacs, and Cory M. Hogaboam. 2003. Mice knockouts for chemokines and chemokine receptors. In Giamila Fantuzzi (Ed.), Cytokine Knockouts, second edition. Totowa, NJ: Humana Press, p. 323-45.

• Cory M. Hogaboam, Jane M. Schuh, Alison E. John, and Nicholas W. Lukacs. 2003. The role of chemokines in asthmatic airway responses. In Robert M. Streiter, Steven L. Kunkel, and Theodore J. Standiford (Eds.), Chemokines in the Lung. New York: Marcel Dekker. p. 81-98.

• Cory M. Hogabaom, Kate Blease, and Jane M. Schuh. 2003. Cytokines and chemokines in allergic bronchopulmonary aspergillosis (ABPA) and experimental aspergillus-induced allergic airway or asthmatic disease. Frontiers in Bioscience. 8:E147-E156.

PRESENTATIONS 

• “Mold, Chemokines, and Allergy Research: the inspiration of inhalation.” J.M. Schuh (presenter). Pulmonary Research Fellows Conference 2003, Ann Arbor, MI.

• “The Role of C10/CCL6 in a Murine Model of Chronic Fungal Asthma.” J.M. Schuh (presenter), V. Thammavongsa, C. Jakubzick, and C.M. Hogaboam. FASEB Experimental Biology 2003, San Diego, CA.

• “Therapeutic Intrapulmonary Targeting of RANTES/CCL5-Responsive Cells Prevents Chronic Fungal Asthma.” J.M. Schuh (presenter), K. Blease, H. Bruhl, M. Mack, and C.M. Hogaboam. Chemokines Keystone Symposia 2002, Keystone, CO.

• “Linking Innate and Acquired Immunity: responses to the fungus Aspergillus fumigatus.” J.M. Schuh (presenter). Pulmonary Research Fellows Conference 2002, Ann Arbor, MI.

• “CXC Chemokine Receptor-2 is Necessary for the Development and Persistence of Chronic Fungal Asthma in Mice.” J.M. Schuh (presenter), K. Blease, C.M.Hogaboam. FASEB Experimental Biology: translating the genome 2002, New Orleans, LA.

• “Airway Hyperresponsiveness, but not Airway Remodeling, is Attenuated During Chronic Pulmonary Allergic Responses to Aspergillus in CCR4-/- Mice.” J.M. Schuh (presenter), K. Blease, C.M. Hogaboam. FASEB Experimental Biology: translating the genome 2002, New Orleans, LA.

• “Immunomodulation by a Nematode Parasite.” J.M. Schuh (presenter), T.R. Gustad, and M. Robinson. Basic Aspects of Vaccines, Walter Reed Institute of Research Institute 2000, Bethesda, MD.

• “Characterization of an Adult Nematode Immunomodulatory Protein in Heligmosomoides polygyrus,” J.M. Schuh (presenter), T.R. Gustad, and M. Robinson. Joint Society of Parasitology/Society of Protozoologists Conference 2000, San Juan, Puerto Rico.

• "Identification and Production of a Putative Immunomodulatory Molecule Produced by the Adult Stage of a Parasitic Nematode." J.M. Schuh (presenter). Conference of Research Workers in Animal Disease 1999, Chicago, IL.

• "The Immunology of Vaccination Programs." J.M. Schuh (presenter). North Dakota Extension Service Modified Live Vaccine Certification Seminar 1998 and 2000, Bismarck, ND.